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Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ(70) domain 1.1

Bacteriophage T7 encodes an essential inhibitor of the Escherichia coli host RNA polymerase (RNAP), the product of gene 2 (Gp2). We determined a series of X-ray crystal structures of E. coli RNAP holoenzyme with or without Gp2. The results define the structure and location of the RNAP σ(70) subunit...

詳細記述

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書誌詳細
主要な著者: Bae, Brian, Davis, Elizabeth, Brown, Daniel, Campbell, Elizabeth A., Wigneshweraraj, Sivaramesh, Darst, Seth A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856789/
https://ncbi.nlm.nih.gov/pubmed/24218560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314576110
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