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Genome rearrangements caused by interstitial telomeric sequences in yeast

Interstitial telomeric sequences (ITSs) are present in many eukaryotic genomes and are linked to genome instabilities and disease in humans. The mechanisms responsible for ITS-mediated genome instability are not understood in molecular detail. Here, we use a model Saccharomyces cerevisiae system to...

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Détails bibliographiques
Auteurs principaux: Aksenova, Anna Y., Greenwell, Patricia W., Dominska, Margaret, Shishkin, Alexander A., Kim, Jane C., Petes, Thomas D., Mirkin, Sergei M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856781/
https://ncbi.nlm.nih.gov/pubmed/24191060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319313110
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