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Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes.

In eukaryotes, a family of related protein kinases (the ATM family) is involved in regulating cellular responses to DNA damage and telomere length. In the yeast Saccharomyces cerevisiae, two members of this family, TEL1 and MEC1, have functionally redundant roles in both DNA damage repair and telome...

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Bibliographic Details
Main Authors: Craven, Rolf J, Greenwell, Patricia W, Dominska, Margaret, Petes, Thomas D
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462148/
https://ncbi.nlm.nih.gov/pubmed/12072449
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