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Multiple Approaches Converge on the Structure of the Integrin αIIb/β3 Transmembrane Heterodimer

Integrins link the cytoskeleton to the extracellular matrix and regulate key signaling events that coordinate cellular processes such as secretion, migration, and proliferation. A single integrin molecule can exist in a resting state that does not bind extracellular ligands or in an active state tha...

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Bibliographic Details
Main Authors: Metcalf, Douglas G., Kulp, Dan W., Bennett, Joel S., DeGrado, William F.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856686/
https://ncbi.nlm.nih.gov/pubmed/19527732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.032
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