Activation of GABAergic neurons in the interpeduncular nucleus triggers physical nicotine withdrawal symptoms

BACKGROUND: Chronic exposure to nicotine elicits physical dependence in smokers, yet the mechanism and neuroanatomical bases for withdrawal symptoms are unclear. As in humans, rodents undergo physical withdrawal symptoms after cessation from chronic nicotine characterized by increased scratching, he...

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Main Authors: Zhao-Shea, Rubing, Liu, Liwang, Pang, Xueyan, Gardner, Paul D., Tapper, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855889/
https://ncbi.nlm.nih.gov/pubmed/24239118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.09.041
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