Functional Upregulation of α4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine Reward

Chronic nicotine exposure increases sensitivity to nicotine reward during a withdrawal period, which may facilitate relapse in abstinent smokers, yet the molecular neuroadaptation(s) that contribute to this phenomenon are unknown. Interestingly, chronic nicotine use induces functional upregulation o...

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Publicado en:J Neurosci
Autores principales: Ngolab, Jennifer, Liu, Liwang, Zhao-Shea, Rubing, Gao, Guangping, Gardner, Paul D., Tapper, Andrew R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588598/
https://ncbi.nlm.nih.gov/pubmed/26041923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4453-14.2015
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