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Structure of the β-form of human MK2 in complex with the non-selective kinase inhibitor TEI-L03090

Mitogen-activated protein kinase-activated protein kinase 2 (MK2 or MAPKAP-K2), a serine/threonine kinase from the p38 mitogen-activated protein kinase signalling pathway, plays an important role in the production of TNF-α and other cytokines. In a previous report, it was shown that MK2 in complex w...

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Detalhes bibliográficos
Main Authors: Fujino, Aiko, Fukushima, Kei, Kubota, Takaharu, Matsumoto, Yoshiyuki, Takimoto-Kamimura, Midori
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855716/
https://ncbi.nlm.nih.gov/pubmed/24316826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113030534
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