ADENO-ASSOCIATED VIRUS TYPE 6 IS RETROGRADELY TRANSPORTED IN THE NON-HUMAN PRIMATE BRAIN

We recently demonstrated that axonal transport of adeno-associated virus (AAV) is serotype-dependent. Thus, AAV2 is anterogradely transported (e.g., from cell bodies to nerve terminals) in both rat and non-human primate (NHP) brain. In contrast, AAV6 is retrogradely transported from terminals to neu...

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Hauptverfasser: Sebastian, Waldy San, Samaranch, Lluis, Heller, Gregory, Kells, Adrian P., Bringas, John, Pivirotto, Phillip, Forsayeth, John, Bankiewicz, Krystof S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855617/
https://ncbi.nlm.nih.gov/pubmed/24067867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.48
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