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Mycobacterial MazG Safeguards Genetic Stability via Housecleaning of 5-OH-dCTP

Generation of reactive oxygen species and reactive nitrogen species in phagocytes is an important innate immune response mechanism to eliminate microbial pathogens. It is known that deoxynucleotides (dNTPs), the precursor nucleotides to DNA synthesis, are one group of the significant targets for the...

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Detalhes bibliográficos
Main Authors: Lyu, Liang-Dong, Tang, Bi-Kui, Fan, Xiao-Yong, Ma, Hui, Zhao, Guo-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855555/
https://ncbi.nlm.nih.gov/pubmed/24339782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003814
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