Mycobacterial MazG Is a Novel NTP Pyrophosphohydrolase Involved in Oxidative Stress Response

MazG nucleoside triphosphate pyrophosphohydrolase (NTP-PPase, EC 3.6.1.8) from the avirulent Mycobacterium tuberculosis H37Ra contains a spontaneous mutation on a highly conserved residue, resulting in an A219E substitution (MtMazG[A219E]). In this work, we show that mycobacterial MazG from either t...

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Detalhes bibliográficos
Main Authors: Lu(吕, Liang-dong, 亮东), Sun(孙, Qing, 青), Fan(范, Xiao-yong, 小勇), Zhong(钟, Yi, 怡), Yao(姚, Yu-feng, 玉峰), Zhao(赵, Guo-Ping, 国屏)
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934672/
https://ncbi.nlm.nih.gov/pubmed/20529853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088872
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