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Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein

The formation of toxic aggregates composed largely of the protein α-synuclein are a hallmark of Parkinson’s disease. Evidence from both early-onset forms of the disease in humans and animal models has shown that the progression of the disease is correlated with the expression levels of α-synuclein,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Abeywardana, Tharindumala, Lin, Yu Hsuan, Rott, Ruth, Engelender, Simone, Pratt, Matthew R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855323/
https://ncbi.nlm.nih.gov/pubmed/24210006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.09.009
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