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Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein
The formation of toxic aggregates composed largely of the protein α-synuclein are a hallmark of Parkinson’s disease. Evidence from both early-onset forms of the disease in humans and animal models has shown that the progression of the disease is correlated with the expression levels of α-synuclein,...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855323/ https://ncbi.nlm.nih.gov/pubmed/24210006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.09.009 |
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