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Generating gene knockout rats by homologous recombination in embryonic stem cells

We describe here a detailed protocol for generating gene knockout rats by homologous recombination in embryonic stem (ES) cells. This protocol comprises the following procedures: derivation and expansion of rat ES cells, construction of gene-targeting vectors, generation of gene-targeted rat ES cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tong, Chang, Huang, Guanyi, Ashton, Charles, Li, Ping, Ying, Qi-Long
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855261/
https://ncbi.nlm.nih.gov/pubmed/21637202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.338
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