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Rapid and Cost-Effective Gene Targeting in Rat Embryonic Stem Cells by TALENs
The rat is the preferred animal model in many areas of biomedical research and drug development. Genetic manipulation in rats has lagged behind that in mice due to the lack of efficient gene targeting tools. Previously, we generated a knockout rat via conventional homologous recombination in rat emb...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856761/ https://ncbi.nlm.nih.gov/pubmed/22749015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2012.04.004 |
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