Direct atomic force microscope imaging of EcoRI endonuclease site specifically bound to plasmid DNA molecules.

Direct imaging with the atomic force microscope has been used to identify specific nucleotide sequences in plasmid DNA molecules. This was accomplished using EcoRI (Gln-111), a mutant of the restriction enzyme that has a 1000-fold greater binding affinity than the wild-type enzyme but with cleavage...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Allison, D P, Kerper, P S, Doktycz, M J, Spain, J A, Modrich, P, Larimer, F W, Thundat, T, Warmack, R J
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1996
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.8826
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