Peptide lipidation stabilizes structure to enhance biological function()

Medicines that decrease body weight and restore nutrient tolerance could improve human diabetes and obesity treatment outcomes. We developed lipid–acylated glucagon analogs that are co-agonists for the glucagon and glucagon-like peptide 1 receptors, and stimulate weight loss and plasma glucose lower...

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Detalhes bibliográficos
Main Authors: Ward, Brian P., Ottaway, Nickki L., Perez-Tilve, Diego, Ma, Dejian, Gelfanov, Vasily M., Tschöp, Matthias H., DiMarchi, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854995/
https://ncbi.nlm.nih.gov/pubmed/24327962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.08.008
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