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A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction
Structure–function studies have analyzed substitutions within the glucagon-like peptide-1 (GLP-1) sequence that increase resistance to proteolysis, however, the investigation into how such substitutions alter interactions at the GLP-1 receptor (GLP-1R) has captured less attention. This work describe...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817388/ https://ncbi.nlm.nih.gov/pubmed/24199154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.01.003 |
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