Peptide lipidation stabilizes structure to enhance biological function()

Medicines that decrease body weight and restore nutrient tolerance could improve human diabetes and obesity treatment outcomes. We developed lipid–acylated glucagon analogs that are co-agonists for the glucagon and glucagon-like peptide 1 receptors, and stimulate weight loss and plasma glucose lower...

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Autors principals: Ward, Brian P., Ottaway, Nickki L., Perez-Tilve, Diego, Ma, Dejian, Gelfanov, Vasily M., Tschöp, Matthias H., DiMarchi, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854995/
https://ncbi.nlm.nih.gov/pubmed/24327962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.08.008
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