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Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine
Asparagine synthetase (AS) catalyzes the ATP-dependent conversion of aspartate into asparagine using ammonia or glutamine as nitrogen source. There are two distinct types of AS, asparagine synthetase A (AS-A), known as strictly ammonia-dependent, and asparagine synthetase B (AS-B), which can use eit...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854871/ https://ncbi.nlm.nih.gov/pubmed/24340117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002578 |
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