Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity

A growing interest in asparagine (Asn) metabolism has currently been observed in cancer and infection fields. Asparagine synthetase (AS) is responsible for the conversion of aspartate into Asn in an ATP-dependent manner, using ammonia or glutamine as a nitrogen source. There are two structurally dis...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: Faria, Joana, Loureiro, Inês, Santarém, Nuno, Macedo-Ribeiro, Sandra, Tavares, Joana, Cordeiro-da-Silva, Anabela
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714757/
https://ncbi.nlm.nih.gov/pubmed/26771178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004365
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