Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

Current treatments for African trypanosomiasis are either toxic, costly, difficult to administer, or prone to elicit resistance. This study evaluated the activity of bisnaphthalimidopropyl (BNIP) derivatives against Trypanosoma brucei. BNIPDiaminobutane (BNIPDabut), the most active of these compound...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Graça, Nuno A. G., Gaspar, Luis, Costa, David M., Loureiro, Inês, Thoo-Lin, Paul Kong, Ramos, Isbaal, Roura, Meritxell, Pruvost, Alain, Pemberton, Ian K., Loukil, Hadjer, MacDougall, Jane, Tavares, Joana, Cordeiro-da-Silva, Anabela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808195/
https://ncbi.nlm.nih.gov/pubmed/26787703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02490-15
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