Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

Current treatments for African trypanosomiasis are either toxic, costly, difficult to administer, or prone to elicit resistance. This study evaluated the activity of bisnaphthalimidopropyl (BNIP) derivatives against Trypanosoma brucei. BNIPDiaminobutane (BNIPDabut), the most active of these compound...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Graça, Nuno A. G., Gaspar, Luis, Costa, David M., Loureiro, Inês, Thoo-Lin, Paul Kong, Ramos, Isbaal, Roura, Meritxell, Pruvost, Alain, Pemberton, Ian K., Loukil, Hadjer, MacDougall, Jane, Tavares, Joana, Cordeiro-da-Silva, Anabela
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808195/
https://ncbi.nlm.nih.gov/pubmed/26787703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02490-15
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