Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

Current treatments for African trypanosomiasis are either toxic, costly, difficult to administer, or prone to elicit resistance. This study evaluated the activity of bisnaphthalimidopropyl (BNIP) derivatives against Trypanosoma brucei. BNIPDiaminobutane (BNIPDabut), the most active of these compound...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Graça, Nuno A. G., Gaspar, Luis, Costa, David M., Loureiro, Inês, Thoo-Lin, Paul Kong, Ramos, Isbaal, Roura, Meritxell, Pruvost, Alain, Pemberton, Ian K., Loukil, Hadjer, MacDougall, Jane, Tavares, Joana, Cordeiro-da-Silva, Anabela
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808195/
https://ncbi.nlm.nih.gov/pubmed/26787703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02490-15
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