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A Sequential Vesicle Pool Model with a Single Release Sensor and a Ca(2+)-Dependent Priming Catalyst Effectively Explains Ca(2+)-Dependent Properties of Neurosecretion
Neurotransmitter release depends on the fusion of secretory vesicles with the plasma membrane and the release of their contents. The final fusion step displays higher-order Ca(2+) dependence, but also upstream steps depend on Ca(2+). After deletion of the Ca(2+) sensor for fast release – synaptotagm...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854459/ https://ncbi.nlm.nih.gov/pubmed/24339761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003362 |
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