Synaptotagmin Interaction with SNAP-25 Governs Vesicle Docking, Priming, and Fusion Triggering

SNARE complex assembly constitutes a key step in exocytosis that is rendered Ca(2+)-dependent by interactions with synaptotagmin-1. Two putative sites for synaptotagmin binding have recently been identified in SNAP-25 using biochemical methods: one located around the center and another at the C-term...

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Main Authors: Mohrmann, Ralf, de Wit, Heidi, Connell, Emma, Pinheiro, Paulo S., Leese, Charlotte, Bruns, Dieter, Davletov, Bazbek, Verhage, Matthijs, Sørensen, Jakob B.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104293/
https://ncbi.nlm.nih.gov/pubmed/24005294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1236-13.2013
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