Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca(2+) channel distances

Chemical synaptic transmission relies on the Ca(2+)-induced fusion of transmitter-laden vesicles whose coupling distance to Ca(2+) channels determines synaptic release probability and short-term plasticity, the facilitation or depression of repetitive responses. Here, using electron- and super-resol...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kobbersmed, Janus RL, Grasskamp, Andreas T, Jusyte, Meida, Böhme, Mathias A, Ditlevsen, Susanne, Sørensen, Jakob Balslev, Walter, Alexander M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145420/
https://ncbi.nlm.nih.gov/pubmed/32077852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51032
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