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A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data
BACKGROUND: Knowledge of which genes are essential to the survival of an organism is critical to understanding the function of genes, and for the identification of potential drug targets for antimicrobial treatment. Previous statistical methods for assessing essentiality based on sequencing of tranp...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2013
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854130/ https://ncbi.nlm.nih.gov/pubmed/24103077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-303 |
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