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Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries
Motivation: Next-generation sequencing affords an efficient analysis of transposon insertion libraries, which can be used to identify essential genes in bacteria. To analyse this high-resolution data, we present a formal Bayesian framework for estimating the posterior probability of essentiality for...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597147/ https://ncbi.nlm.nih.gov/pubmed/23361328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt043 |
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