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NORMALIZATION OF TRANSPOSON-MUTANT LIBRARY SEQUENCING DATASETS TO IMPROVE IDENTIFICATION OF CONDITIONALLY ESSENTIAL GENES
Sequencing of transposon-mutant libraries using next-generation sequencing (TnSeq) has become a popular method for determining which genes and non-coding regions are essential for growth under various conditions in bacteria. For methods that rely on quantitative comparison of counts of reads at tran...
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| Udgivet i: | J Bioinform Comput Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654600/ https://ncbi.nlm.nih.gov/pubmed/26932272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S021972001642004X |
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