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Recombinant proteins produced into yolk of genetically manipulated chickens are partly sialylated in N-glycan
The transgenic chicken is a candidate for the production of biopharmaceutical proteins with several economic superiorities. In general, the addition of sialic acid at the terminal of N-glycan is important for the bioactivity of biopharmaceuticals including plasma half-life; however, sialic acid has...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Netherlands
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853628/ https://ncbi.nlm.nih.gov/pubmed/23868388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9613-z |
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