High-Level Expression of Single-Chain Fv-Fc Fusion Protein in Serum and Egg White of Genetically Manipulated Chickens by Using a Retroviral Vector

We report here the generation of transgenic chickens using a retroviral vector for the production of recombinant proteins. It was found that the transgene expression was suppressed when a Moloney murine leukemia virus-based retroviral vector was injected into chicken embryos at the blastodermal stag...

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Bibliographic Details
Main Authors: Kamihira, Masamichi, Ono, Ken-ichiro, Esaka, Kazuhisa, Nishijima, Ken-ichi, Kigaku, Ryoko, Komatsu, Hiroyuki, Yamashita, Takashi, Kyogoku, Kenji, Iijima, Shinji
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Gene Delivery
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193598/
https://ncbi.nlm.nih.gov/pubmed/16103139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.10864-10874.2005
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