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Head and neck irradiation modulates pharmacokinetics of 5-fluorouracil and cisplatin
BACKGROUND: 5-fluorouracil (5-FU) and cisplatin (CDDP) are used to enhance radiotherapy (RT) effect for head and neck (HN) cancers. However, the effect of local RT on systemic chemotherapeutics remains unclear. Here, we evaluated the influence of HN irradiation on the pharmacokinetics (PK) of 5-FU a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853440/ https://ncbi.nlm.nih.gov/pubmed/24066670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-231 |
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