Abdominal irradiation modulates 5-Fluorouracil pharmacokinetics

BACKGROUND: Concurrent chemoradiation with 5-fluorouracil (5-FU) is widely accepted for treatment of abdominal malignancy. Nonetheless, the interactions between radiation and 5-FU remain unclear. We evaluated the influence of abdominal irradiation on the pharmacokinetics of 5-FU in rats. METHODS: Th...

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Bibliografiske detaljer
Main Authors: Hsieh, Chen-Hsi, Hsieh, Yen-Ju, Liu, Chia-Yuan, Tai, Hung-Chi, Huang, Yu-Chuen, Shueng, Pei-Wei, Wu, Le-Jung, Wang, Li-Ying, Tsai, Tung-Hu, Chen, Yu-Jen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861020/
https://ncbi.nlm.nih.gov/pubmed/20338060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-29
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