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Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential

KDM4 histone demethylases catalyze the removal of methyl marks from histone lysine residues to epigenetically regulate chromatin structure and gene expression. KDM4 expression is tightly regulated to insure proper function in diverse biological processes, such as cellular differentiation. Mounting e...

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Autors principals: Labbé, Roselyne M, Holowatyj, Andreana, Yang, Zeng-Quan
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853420/
https://ncbi.nlm.nih.gov/pubmed/24349617
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