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Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy
BACKGROUND: The childhood neuromuscular disease spinal muscular atrophy (SMA) is caused by mutations or deletions of the survival motor neuron (SMN1) gene. Although SMA has traditionally been considered a motor neuron disease, the muscle-specific requirement for SMN has never been fully defined. The...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852932/ https://ncbi.nlm.nih.gov/pubmed/24119341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-24 |
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