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Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy
BACKGROUND: The childhood neuromuscular disease spinal muscular atrophy (SMA) is caused by mutations or deletions of the survival motor neuron (SMN1) gene. Although SMA has traditionally been considered a motor neuron disease, the muscle-specific requirement for SMN has never been fully defined. The...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852932/ https://ncbi.nlm.nih.gov/pubmed/24119341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-24 |
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