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Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy
Mutations in the survival motor neuron (SMN1) gene lead to the neuromuscular disease spinal muscular atrophy (SMA). Although SMA is primarily considered as a motor neuron disease, the importance of muscle defects in its pathogenesis has not been fully examined. We use both primary cell culture and t...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103674/ https://ncbi.nlm.nih.gov/pubmed/24691550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu142 |
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