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A Novel Series of Piperidin-4-yl-1,3-Dihydroindol-2-ones as Agonist and Antagonist Ligands at the Nociceptin Receptor

A series of N-(4-piperidinyl)-2-indolinones were discovered as a new structural class of nociceptin receptor (NOP) ligands. Unlike other previously reported classes of NOP receptor ligands, modifications of the piperidine N substituents afforded both potent agonists and antagonists, with modest sele...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zaveri, Nurulain T., Jiang, Faming, Olsen, Cris M., Deschamps, Jeffrey R., Parrish, Damon, Polgar, Willma, Toll, Lawrence
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852901/
https://ncbi.nlm.nih.gov/pubmed/15163178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm034249d
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