Designing Bifunctional NOP receptor-mu opioid receptor ligands from NOP receptor-selective scaffolds. Part I

The nociceptin receptor (NOP) and its endogenous agonist, nociceptin/Orphanin FQ (N/OFQ), members of the opioid receptor and peptide families respectively, modulate the pharmacological effects of classical opioids, particularly opioid-induced reward and nociception. We hypothesized that compounds co...

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Hlavní autoři: Zaveri, Nurulain, Jiang, Faming, Olsen, Cris, Polgar, Willma, Toll, Lawrence
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651809/
https://ncbi.nlm.nih.gov/pubmed/23623415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.03.101
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