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Crystal Structure of the Cataract-Causing P23T γD-Crystallin Mutant

Up to now, efforts to crystallize the cataract-associated P23T mutant of human γD-crystallin have not been successful. Therefore, insights into the light scattering mechanism of this mutant have been exclusively obtained from solution work. Here we present the first crystal structure of the P23T mut...

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Hlavní autoři: Ji, Fangling, Koharudin, Leonardus M. I., Jung, Jinwon, Gronenborn, Angela M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852438/
https://ncbi.nlm.nih.gov/pubmed/23670788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24321
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