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Roles of Chk1 in Cell Biology and Cancer Therapy
The evolutionally conserved DNA damage response (DDR) and cell cycle checkpoints preserve genome integrity. Central to these genome surveillance pathways is a protein kinase, Chk1. DNA damage induces activation of Chk1, which then transduces the checkpoint signal and facilitates cell cycle arrest an...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852170/ https://ncbi.nlm.nih.gov/pubmed/23613359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28226 |
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