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Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

One classical feature of cancer cells is their metabolic acquisition of a highly glycolytic phenotype. Carbon monoxide (CO), one of the products of the cytoprotective molecule heme oxygenase-1 (HO-1) in cancer cells, has been implicated in carcinogenesis and therapeutic resistance. However, the func...

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Main Authors: Wegiel, Barbara, Gallo, David, Csizmadia, Eva, Harris, Clair, Belcher, John, Vercellotti, Gregory M., Penacho, Nuno, Seth, Pankaj, Sukhatme, Vikas, Ahmed, Asif, Pandolfi, Pier Paolo, Helczynski, Leszek, Bjartell, Anders, Persson, Jenny Liao, Otterbein, Leo E
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851591/
https://ncbi.nlm.nih.gov/pubmed/24121491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1075
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