Lincomycin Biosynthesis Involves a Tyrosine Hydroxylating Heme Protein of an Unusual Enzyme Family

The gene lmbB2 of the lincomycin biosynthetic gene cluster of Streptomyces lincolnensis ATCC 25466 was shown to code for an unusual tyrosine hydroxylating enzyme involved in the biosynthetic pathway of this clinically important antibiotic. LmbB2 was expressed in Escherichia coli, purified near to ho...

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Detalles Bibliográficos
Autores principales: Novotna, Jitka, Olsovska, Jana, Novak, Petr, Mojzes, Peter, Chaloupkova, Radka, Kamenik, Zdenek, Spizek, Jaroslav, Kutejova, Eva, Mareckova, Marketa, Tichy, Pavel, Damborsky, Jiri, Janata, Jiri
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851162/
https://ncbi.nlm.nih.gov/pubmed/24324587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079974
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