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Clues to the Function of the Tumour Susceptibility Gene BRCA2

The breast cancer susceptibility gene BRCA2 was isolated in 1995. BRCA2 is a large gene comprising 10,254 nucleotides and 26 coding exons. Neither the nucleotide nor the predicted protein sequences (comprising 3,418 amino acids) have provided substantial clues about its function. As a result, resear...

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Autori principali: Gayther, Simon A., Ponder, Bruce A. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850562/
https://ncbi.nlm.nih.gov/pubmed/9706457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1998/613765
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