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Neuropathy Target Esterase Is Required for Adult Vertebrate Axon Maintenance

The enzyme neuropathy target esterase (NTE) is present in neurons and deacylates the major membrane phospholipid, phosphatidylcholine (PtdCho). Mutation of the NTE gene or poisoning by neuropathic organophosphates—chemical inhibitors of NTE—causes distal degeneration of long spinal axons in humans....

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Bibliografiske detaljer
Main Authors: Read, David J., Li, Yong, Chao, Moses V., Cavanagh, John B., Glynn, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849655/
https://ncbi.nlm.nih.gov/pubmed/19759306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3007-09.2009
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