Neuropathy Target Esterase Is Required for Adult Vertebrate Axon Maintenance

The enzyme neuropathy target esterase (NTE) is present in neurons and deacylates the major membrane phospholipid, phosphatidylcholine (PtdCho). Mutation of the NTE gene or poisoning by neuropathic organophosphates—chemical inhibitors of NTE—causes distal degeneration of long spinal axons in humans....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Read, David J., Li, Yong, Chao, Moses V., Cavanagh, John B., Glynn, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2009
Pynciau:
Brief Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849655/
https://ncbi.nlm.nih.gov/pubmed/19759306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3007-09.2009
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