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Neuropathy Target Esterase Is Required for Adult Vertebrate Axon Maintenance
The enzyme neuropathy target esterase (NTE) is present in neurons and deacylates the major membrane phospholipid, phosphatidylcholine (PtdCho). Mutation of the NTE gene or poisoning by neuropathic organophosphates—chemical inhibitors of NTE—causes distal degeneration of long spinal axons in humans....
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849655/ https://ncbi.nlm.nih.gov/pubmed/19759306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3007-09.2009 |
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