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Neuropathy Target Esterase Is Required for Adult Vertebrate Axon Maintenance

The enzyme neuropathy target esterase (NTE) is present in neurons and deacylates the major membrane phospholipid, phosphatidylcholine (PtdCho). Mutation of the NTE gene or poisoning by neuropathic organophosphates—chemical inhibitors of NTE—causes distal degeneration of long spinal axons in humans....

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Detalhes bibliográficos
Main Authors: Read, David J., Li, Yong, Chao, Moses V., Cavanagh, John B., Glynn, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849655/
https://ncbi.nlm.nih.gov/pubmed/19759306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3007-09.2009
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