Evidence of Genetic Interaction between the β-Globin Complex and Chromosome 8q in the Expression of Fetal Hemoglobin

During human development, the switch from fetal to adult hemoglobin (Hb) is not complete with the residual γ-globin expression being restricted to a subset of erythrocytes termed “F cells” (FC). Statistical analyses have shown the FC trait to be influenced by a common sequence variant (C→T) at posit...

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Hlavní autoři: Garner, Chad P., Tatu, Thanusak, Best, Steve, Creary, Lisa, Thein, Swee Lay
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384958/
https://ncbi.nlm.nih.gov/pubmed/11822023
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