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Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors
Homo-pentameric Cys-loop receptors contain five identical agonist binding sites, each formed at a subunit interface. To determine the number and locations of binding sites required to generate a stable active state, we constructed a receptor subunit with a mutation that disables the agonist binding...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849470/ https://ncbi.nlm.nih.gov/pubmed/19420269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0627-09.2009 |
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