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Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts
RNA is an important yet vastly underexploited target for small molecule chemical probes or lead therapeutics. Small molecules have been used successfully to modulate the function of the bacterial ribosome, viral RNAs and riboswitches. These RNAs are either highly expressed or can be targeted using s...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849211/ https://ncbi.nlm.nih.gov/pubmed/23939337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.07.024 |
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